Ontology highlight
ABSTRACT:
SUBMITTER: Calvo AC
PROVIDER: S-EPMC4137497 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Calvo Ana C AC Manzano Raquel R Mendonça Deise M F DM Muñoz María J MJ Zaragoza Pilar P Osta Rosario R
BioMed research international 20140803
Since amyotrophic lateral sclerosis (ALS) was discovered and described in 1869 as a neurodegenerative disease in which motor neuron death is induced, a wide range of biomarkers have been selected to identify therapeutic targets. ALS shares altered molecular pathways with other neurodegenerative diseases, such as Alzheimer's, Huntington's, and Parkinson's diseases. However, the molecular targets that directly influence its aggressive nature remain unknown. What is the first link in the neurodegen ...[more]