Ontology highlight
ABSTRACT:
SUBMITTER: Rutkove SB
PROVIDER: S-EPMC4404434 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20150401 2
Progressive weakness remains the clinical hallmark of amyotrophic lateral sclerosis (ALS). Accordingly, a variety of tools has been developed to capture this disease feature, including questionnaires, such as the ALS-functional rating scale, strength testing, pulmonary function tests, electrophysiologic measures, including motor unit number estimation, and imaging techniques. Despite this plethora of approaches, there is little agreement as to what measures to use in a given clinical trial or in ...[more]