C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog.
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ABSTRACT:
SUBMITTER: Rabe S
PROVIDER: S-EPMC4142839 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog.
Rabe Sebastian S Moschner Johann J Bantzi Marina M Heretsch Philipp P Giannis Athanassios A
Beilstein journal of organic chemistry 20140709
The chemical synthesis of carbacyclopamine analog 2, a cyclopamine analog with an all-carbon E-ring, is reported. The use of C-H-functionalization logic and further metal-catalyzed transformations allows for a concise entry to this new class of acid-stable cyclopamine analogs. ...[more]
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