Ontology highlight
ABSTRACT:
SUBMITTER: Chin CR
PROVIDER: S-EPMC4145670 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Chin Christopher R CR Brass Abraham L AL
Methods (San Diego, Calif.) 20121002 2
The use of genome wide RNA interference (RNAi) screens to investigate host-virals interactions has revealed unexpected connections that have improved our understanding of viral pathogenesis and cell biology. This work describes the use of an RNAi screening method employing an immunofluorescence image-based strategy and influenza A virus. We find this approach to be readily implemented, scalable and amenable to the direct evaluation of a variety of viral lifecycles. ...[more]