Ontology highlight
ABSTRACT:
SUBMITTER: Gopal A
PROVIDER: S-EPMC4154850 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Gopal Ajaykumar A Egecioglu Defne E DE Yoffe Aron M AM Ben-Shaul Avinoam A Rao Ayala L N AL Knobler Charles M CM Gelbart William M WM
PloS one 20140904 9
A majority of viruses are composed of long single-stranded genomic RNA molecules encapsulated by protein shells with diameters of just a few tens of nanometers. We examine the extent to which these viral RNAs have evolved to be physically compact molecules to facilitate encapsulation. Measurements of equal-length viral, non-viral, coding and non-coding RNAs show viral RNAs to have among the smallest sizes in solution, i.e., the highest gel-electrophoretic mobilities and the smallest hydrodynamic ...[more]