Chemoprevention in patients with genetic risk of colorectal cancers.
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ABSTRACT:
SUBMITTER: Laukaitis CM
PROVIDER: S-EPMC4162131 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Chemoprevention in patients with genetic risk of colorectal cancers.
Laukaitis Christina M CM Erdman Steven H SH Gerner Eugene W EW
Colorectal cancer 20120101 3
A number of genetic syndromes are known to convey a high risk of colorectal cancer. Current standards of medical practice for these patients involve genetic testing followed by screening and surgical procedures. Pharmaceutical therapies for any of these syndromes are limited in number and are generally not approved by any regulatory body for applications in these genetic groups. This review discusses advances in mechanistic understanding of the disease processes leading to the development of pro ...[more]
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