Ontology highlight
ABSTRACT:
SUBMITTER: Jun Y
PROVIDER: S-EPMC4167536 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Biophysical journal 20140901 6
There is significant interest in quantifying force production inside cells, but since conditions in vivo are less well controlled than those in vitro, in vivo measurements are challenging. In particular, the in vivo environment may vary locally as far as its optical properties, and the organelles manipulated by the optical trap frequently vary in size and shape. Several methods have been proposed to overcome these difficulties. We evaluate the relative merits of these methods and directly compar ...[more]