Developmental trajectories of Body Mass Index from infancy to 18 years of age: prenatal determinants and health consequences.

ABSTRACT:

Background

Knowledge on the long-term development of adiposity throughout childhood/adolescence and its prenatal determinants and health sequelae is lacking. We sought to (1) identify trajectories of Body Mass Index (BMI) from 1 to 18 years of age, (2) examine associations of maternal gestational smoking and early pregnancy overweight with offspring BMI trajectories and (3) determine whether BMI trajectories predict health outcomes: asthma, lung function parameters (forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio), and blood pressure, at 18 years.

Methods

The Isle of Wight birth cohort, a population-based sample of 1456 infants born between January 1989 and February 1990, was prospectively assessed at ages 1, 2, 4, 10 and 18 years. Group-based

SUBMITTER: Ziyab AH 

PROVIDER: S-EPMC4174013 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature