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Crystal structure of 2-(2-bromo-phen-yl)-4-(1H-indol-3-yl)-6-(thio-phen-2-yl)pyridine-3-carbo-nitrile.

ABSTRACT: In the title compound, C24H14BrN3S, the dihedral angles between the planes of the pyridine ring and the pendant thio-phene ring, the indole ring system (r.m.s. deviation = 0.022?Å) and the bromo-benzene ring are 9.37?(17), 21.90?(12) and 69.01?(15)°, respectively. The approximate coplanarity of the central ring and the indole ring system is supported by two intra-molecular C-H?N inter-actions. In the crystal, inversion dimers linked by pairs of N-H?N hydrogen bonds generate R 2 (2)(16) loops and the dimers are linked by C-H?? and aromatic ?-? stacking [shortest centroid-centroid separation = 3.729?(3)?Å] into a three-dimensional network.

SUBMITTER: Vishnupriya R

PROVIDER: S-EPMC4186133 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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Crystal structure of 2-(2-bromo-phen-yl)-4-(1H-indol-3-yl)-6-(thio-phen-2-yl)pyridine-3-carbo-nitrile.

Vishnupriya R R Suresh J J Bharkavi Shanmugavel S Perumal Subbu S Lakshman P L Nilantha PL

Acta crystallographica. Section E, Structure reports online 20140801 Pt 9

In the title compound, C24H14BrN3S, the dihedral angles between the planes of the pyridine ring and the pendant thio-phene ring, the indole ring system (r.m.s. deviation = 0.022 Å) and the bromo-benzene ring are 9.37 (17), 21.90 (12) and 69.01 (15)°, respectively. The approximate coplanarity of the central ring and the indole ring system is supported by two intra-molecular C-H⋯N inter-actions. In the crystal, inversion dimers linked by pairs of N-H⋯N hydrogen bonds generate R 2 (2)(16) loops and ...[more]

PMID: 25309284

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