Ontology highlight
ABSTRACT:
SUBMITTER: Hill JE
PROVIDER: S-EPMC4207532 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Journal of medicinal chemistry 20141001 20
We examined a series of selenorhodamines with amide and thioamide functionality at the 5-position of a 9-(2-thienyl) substituent on the selenorhodamine core for their potential as photosensitizers for photodynamic therapy (PDT) in P-glycoprotein (P-gp) expressing cells. These compounds were examined for their photophysical properties (absorption, fluorescence, and ability to generate singlet oxygen), for their uptake into Colo-26 cells in the absence or presence of verapamil, for their dark and ...[more]