Dataset Information
Feasibility and initial effectiveness of home exercise during maintenance therapy for childhood acute lymphoblastic leukemia.
Ontology highlight
ABSTRACT: Purpose
Children with acute lymphoblastic leukemia (ALL) are at increased risk of obesity and deconditioning from cancer therapy. This pilot study assessed feasibility/initial efficacy of an exercise intervention for patients with ALL undergoing maintenance therapy.Methods
Participants were aged 5 to 10 years, receiving maintenance therapy, in first remission. A 6-month home-based intervention, with written and video instruction, was supervised with weekly calls from an exercise coach. Pre- and poststudy testing addressed strength, flexibility, fitness, and motor function.Results
Seventeen patients enrolled (participation 63%). Twelve (71%) finished the intervention, completing 81.7 ± 7.2% of prescribed sessions. Improvements of 5% or more occurred in 67% for knee and 75% for grip strength, 58% for hamstring/low-back and 83% for ankle flexibility, 75% for the 6-Minute Walk Test, and 33% for performance on the Bruininks-Oseretsky Test of Motor Proficiency Version 2.Conclusions
This pilot study demonstrated that exercise intervention during ALL therapy is feasible and has promise for efficacy.
SUBMITTER: Esbenshade AJ
PROVIDER: S-EPMC4211618 | biostudies-literature | 2014 Fall
REPOSITORIES: biostudies-literature
Publications
Feasibility and initial effectiveness of home exercise during maintenance therapy for childhood acute lymphoblastic leukemia.
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association 20140901 3
<h4>Purpose</h4>Children with acute lymphoblastic leukemia (ALL) are at increased risk of obesity and deconditioning from cancer therapy. This pilot study assessed feasibility/initial efficacy of an exercise intervention for patients with ALL undergoing maintenance therapy.<h4>Methods</h4>Participants were aged 5 to 10 years, receiving maintenance therapy, in first remission. A 6-month home-based intervention, with written and video instruction, was supervised with weekly calls from an exercise ...[more]
