Ontology highlight
ABSTRACT:
SUBMITTER: Song X
PROVIDER: S-EPMC4212054 | biostudies-literature | 2015 Jan-Feb
REPOSITORIES: biostudies-literature
Contrast media & molecular imaging 20140428 1
Diamagnetic chemical exchange saturation transfer (diaCEST) agents are a new class of imaging agents, which have unique magnetic resonance (MR) properties similar to agents used for optical imaging. Here we present a series of anthranilic acid analogs as examples of diaCEST agents that feature an exchangeable proton shifted downfield, namely, an intramolecular-bond shifted hydrogen (IM-SHY), which produces significant and tunable contrast at frequencies of 4.8-9.3 ppm from water. Five analogs of ...[more]