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Radical C-H functionalization of heteroarenes under electrochemical control.


ABSTRACT: Electrochemical reactions are shown to be effective for the C-H functionalization of a number of heterocyclic substrates that are recalcitrant to conventional peroxide radical initiation conditions. Monitoring reaction progress under electrochemical conditions provides mechanistic insight into the C-H functionalization of a series of heterocycles of interest in medicinal chemistry.

SUBMITTER: O'Brien AG 

PROVIDER: S-EPMC4214156 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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