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Reductive cross-coupling of 3-bromo-2,1-borazaronaphthalenes with alkyl iodides.


ABSTRACT: Conditions have been developed for the reductive cross-coupling of 3-bromo-2,1-borazaronaphthalenes with primary and secondary alkyl iodides. This method allows direct alkylation of azaborine cores, providing efficient access to functionalized isosteres of naphthalene derivatives.

SUBMITTER: Molander GA 

PROVIDER: S-EPMC4216191 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Reductive cross-coupling of 3-bromo-2,1-borazaronaphthalenes with alkyl iodides.

Molander Gary A GA   Wisniewski Steven R SR   Traister Kaitlin M KM  

Organic letters 20140630 14


Conditions have been developed for the reductive cross-coupling of 3-bromo-2,1-borazaronaphthalenes with primary and secondary alkyl iodides. This method allows direct alkylation of azaborine cores, providing efficient access to functionalized isosteres of naphthalene derivatives. ...[more]

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