Ontology highlight
ABSTRACT:
SUBMITTER: Kungulovski G
PROVIDER: S-EPMC4216925 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Genome research 20141009 11
Post-translational modifications (PTMs) of histones constitute a major chromatin indexing mechanism, and their proper characterization is of highest biological importance. So far, PTM-specific antibodies have been the standard reagent for studying histone PTMs despite caveats such as lot-to-lot variability of specificity and binding affinity. Herein, we successfully employed naturally occurring and engineered histone modification interacting domains for detection and identification of histone PT ...[more]