Ontology highlight
ABSTRACT:
SUBMITTER: Macintyre G
PROVIDER: S-EPMC4217187 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Macintyre Geoff G Jimeno Yepes Antonio A Ong Cheng Soon CS Verspoor Karin K
PeerJ 20141023
We present a method to assist in interpretation of the functional impact of intergenic disease-associated SNPs that is not limited to search strategies proximal to the SNP. The method builds on two sources of external knowledge: the growing understanding of three-dimensional spatial relationships in the genome, and the substantial repository of information about relationships among genetic variants, genes, and diseases captured in the published biomedical literature. We integrate chromatin confo ...[more]