A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization.
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ABSTRACT:
SUBMITTER: Fairbanks BD
PROVIDER: S-EPMC4226179 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
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A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization.
Fairbanks Benjamin D BD Schwartz Michael P MP Halevi Alexandra E AE Nuttelman Charles R CR Bowman Christopher N CN Anseth Kristi S KS
Advanced materials (Deerfield Beach, Fla.) 20091007 48
Step-growth, radically mediated thiol-norbornene photopolymerization is used to create versatile, stimuli-responsive poly(ethylene glycol)-co-peptide hydrogels The reaction is cytocompatible and allows for the encapsulation of human mesenchymal stem cells with a viability greater than 95%. Cellular spreading is dictated via three-dimensional biochemical photopatterning. ...[more]
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