Ontology highlight
ABSTRACT:
SUBMITTER: Vaidyanathan U
PROVIDER: S-EPMC4231542 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Vaidyanathan Uma U Malone Stephen M SM Miller Michael B MB McGue Matt M Iacono William G WG
Psychophysiology 20141201 12
Acoustic startle responses have been studied extensively in relation to individual differences and psychopathology. We examined three indices of the blink response in a picture-viewing paradigm-overall startle magnitude across all picture types, and aversive and pleasant modulation scores-in 3,323 twins and parents. Biometric models and molecular genetic analyses showed that half the variance in overall startle was due to additive genetic effects. No single nucleotide polymorphism was genome-wid ...[more]