Ontology highlight
ABSTRACT:
SUBMITTER: Berezney JP
PROVIDER: S-EPMC4231729 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Berezney John P JP Saleh Omar A OA
Nucleic acids research 20140826 19
Single-molecule manipulation (SMM) techniques use applied force, and measured elastic response, to reveal microscopic physical parameters of individual biomolecules and details of biomolecular interactions. A major hurdle in the application of these techniques is the labeling method needed to immobilize biomolecules on solid supports. A simple, minimally-perturbative labeling strategy would significantly broaden the possible applications of SMM experiments, perhaps even allowing the study of nat ...[more]