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Development of a Concise Synthetic Approach to Access Oroxin A.

ABSTRACT: A novel environment-friendly method to access bioactive oroxin A through a one-pot/two-step process from naturally abundant and inexpensive baicalin is described. The procedure presented here has several advantages including clean, one-pot, synthetic ease, and large-scale feasibility. This work also provides a model strategy for rapid and diverse access to natural molecules sharing the common skeleton of this family.

SUBMITTER: Chen H

PROVIDER: S-EPMC4242426 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Development of a Concise Synthetic Approach to Access Oroxin A.

Chen Haijun H He Guihua G Li Cailong C Dong Longrong L Xie Xiaobo X Wu Jianlei J Gao Yu Y Zhou Jia J

RSC advances 20140101 85

A novel environment-friendly method to access bioactive oroxin A through a one-pot/two-step process from naturally abundant and inexpensive baicalin is described. The procedure presented here has several advantages including clean, one-pot, synthetic ease, and large-scale feasibility. This work also provides a model strategy for rapid and diverse access to natural molecules sharing the common skeleton of this family. ...[more]

PMID: 25431654

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