Ontology highlight
ABSTRACT:
SUBMITTER: Viktorovskaya OV
PROVIDER: S-EPMC4272624 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Gene 20141024 1
Eukaryotic cells express at least three unique nuclear RNA polymerases. The selective advantage provided by this enhanced complexity is a topic of fundamental interest in cell biology. It has long been known that the gene targets and transcription initiation pathways for RNA polymerases (Pols) I, II and III are distinct; however, recent genetic, biochemical and structural data suggest that even the core enzymes have evolved unique properties. Among the three eukaryotic RNA polymerases, Pol I is ...[more]