Ontology highlight
ABSTRACT:
SUBMITTER: Rouhanifard SH
PROVIDER: S-EPMC4278937 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Rouhanifard Sara H SH López-Aguilar Aimé A Wu Peng P
Chembiochem : a European journal of chemical biology 20141117 18
The characterization of aberrant glycosylation patterns in biopsied patient samples represents a remarkable challenge for scientists and medical doctors due to the lack of specific methods for detection. Here, we report the development of a histological method, dubbed CHoMP-chemoenzymatic histology of membrane polysaccharides-for analyzing glycosylation patterns in mammalian tissues. This method exploits a recombinant glycosyltransferase to transfer a monosaccharide analogue equipped with a chem ...[more]