Ontology highlight
ABSTRACT:
SUBMITTER: Lavine KJ
PROVIDER: S-EPMC4306353 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Lavine Kory J KJ Long Fanxin F Choi Kyunghee K Smith Craig C Ornitz David M DM
Development (Cambridge, England) 20080901 18
Vascular development begins with formation of a primary capillary plexus that is later remodeled to give rise to the definitive vasculature. Although the mechanism by which arterial and venous fates are acquired is well understood, little is known about when during vascular development arterial and venous vessels emerge and how their growth is regulated. Previously, we have demonstrated that a hedgehog (HH)/vascular endothelial growth factor (VEGF) and angiopoeitin 2 (ANG2) signaling pathway is ...[more]