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A carbohydrate approach for the formal total synthesis of (-)-aspergillide C.

ABSTRACT: An enantioselective formal total synthesis of aspergillide C is accomplished using commercially available tri-O-acetyl-D-galactal employing a Ferrier-type C-glycosylation, utilizing a Trost hydrosilylation and protodesilylation as key reactions.

SUBMITTER: Srihari P

PROVIDER: S-EPMC4311580 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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A carbohydrate approach for the formal total synthesis of (-)-aspergillide C.

Srihari Pabbaraja P Hari Krishna Namballa N Sridhar Ydhyam Y Kamal Ahmed A

Beilstein journal of organic chemistry 20141223

An enantioselective formal total synthesis of aspergillide C is accomplished using commercially available tri-O-acetyl-D-galactal employing a Ferrier-type C-glycosylation, utilizing a Trost hydrosilylation and protodesilylation as key reactions. ...[more]

PMID: 25670981

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