Ontology highlight
ABSTRACT:
SUBMITTER: Lockner JW
PROVIDER: S-EPMC4319694 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Molecular pharmaceutics 20150107 2
Cocaine abuse is problematic, directly and indirectly impacting the lives of millions, and yet existing therapies are inadequate and usually ineffective. A cocaine vaccine would be a promising alternative therapeutic option, but efficacy is hampered by variable production of anticocaine antibodies. Thus, new tactics and strategies for boosting cocaine vaccine immunogenicity must be explored. Flagellin is a bacterial protein that stimulates the innate immune response via binding to extracellular ...[more]