Ontology highlight
ABSTRACT:
SUBMITTER: Van Nuffel AM
PROVIDER: S-EPMC4341996 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Ecancermedicalscience 20150224
Clarithromycin (CAM) is a well-known macrolide antibiotic available as a generic drug. CAM is traditionally used for many types of bacterial infections, treatment of Lyme disease and eradication of gastric infection with Helicobacter pylori. Extensive preclinical and clinical data demonstrate a potential role for CAM to treat various tumours in combination with conventional treatment. The mechanisms of action underlying the anti-tumour activity of CAM are multiple and include prolonged reduction ...[more]