Ontology highlight
ABSTRACT:
SUBMITTER: Pantziarka P
PROVIDER: S-EPMC5931815 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Pantziarka Pan P Sukhatme Vidula V Crispino Sergio S Bouche Gauthier G Meheus Lydie L Sukhatme Vikas P VP
Ecancermedicalscience 20180411
Selective phosphodiesterase 5 inhibitors, including sildenafil, tadalafil and vardenafil, are widely-used in the treatment of erectile dysfunction and pulmonary arterial hypertension. They are also well-known as examples of successful drug repurposing in that they were initially developed for angina and only later developed for erectile dysfunction. However, these drugs may also be effective cancer treatments. A range of evidentiary sources are assessed in this paper and the case made that there ...[more]