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Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine.

ABSTRACT: Four different conjugated polymer nanoparticles (CPNs) were used to differentiate structurally similar glycosaminoglycans (GAGs) in a urine simulant. Unique emission response patterns of CPNs were analyzed by linear discriminant analysis (LDA), confirming that structurally diverse CPNs are sensitive and effective at differentiating GAGs in a complex biological medium.

SUBMITTER: Twomey M

PROVIDER: S-EPMC4342752 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine.

Twomey Megan M Vokatá Tereza T Kumar Manian Rajesh MR Moon Joong Ho JH

Chemical communications (Cambridge, England) 20150301 19

Four different conjugated polymer nanoparticles (CPNs) were used to differentiate structurally similar glycosaminoglycans (GAGs) in a urine simulant. Unique emission response patterns of CPNs were analyzed by linear discriminant analysis (LDA), confirming that structurally diverse CPNs are sensitive and effective at differentiating GAGs in a complex biological medium. ...[more]

PMID: 25659355

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