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Progress in acute myeloid leukemia.

ABSTRACT: Significant progress has been made in the treatment of acute myeloid leukemia (AML). Steady gains in clinical research and a renaissance of genomics in leukemia have led to improved outcomes. The recognition of tremendous heterogeneity in AML has allowed individualized treatments of specific disease entities within the context of patient age, cytogenetics, and mutational analysis. The following is a comprehensive review of the current state of AML therapy and a roadmap of our approach to these distinct disease entities.

SUBMITTER: Kadia TM

PROVIDER: S-EPMC4344862 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Progress in acute myeloid leukemia.

Kadia Tapan M TM Ravandi Farhad F O'Brien Susan S Cortes Jorge J Kantarjian Hagop M HM

Clinical lymphoma, myeloma & leukemia 20140919 3

Significant progress has been made in the treatment of acute myeloid leukemia (AML). Steady gains in clinical research and a renaissance of genomics in leukemia have led to improved outcomes. The recognition of tremendous heterogeneity in AML has allowed individualized treatments of specific disease entities within the context of patient age, cytogenetics, and mutational analysis. The following is a comprehensive review of the current state of AML therapy and a roadmap of our approach to these d ...[more]

PMID: 25441110

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