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Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl-amino]-meth-yl}cyclo-hexa-necarb-oxy-lic acid.

ABSTRACT: The title compound, C18H21NO4S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol-ecules form inversion dimers via O-H?O hydrogen bonds involving the carb-oxy-lic acid groups. Hydrogen bonding between the sulfonamide N-H group and the carb-oxy-lic acid O atom assembles the dimers into thick layers parallel to (100). The naphthalene groups of adjacent layers are arranged in a herring-bone motif. There are C-H?? inter-actions between the naphthalene rings of neighbouring layers.

SUBMITTER: Danish M

PROVIDER: S-EPMC4350692 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl-amino]-meth-yl}cyclo-hexa-necarb-oxy-lic acid.

Danish Muhammad M Tahir Muhammad Nawaz MN Hussain Asif A Ashfaq Muhammad M Sadiq Muhammad Nadeem MN

Acta crystallographica. Section E, Crystallographic communications 20150204 Pt 3

The title compound, C18H21NO4S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol-ecules form inversion dimers via O-H⋯O hydrogen bonds involving the carb-oxy-lic acid groups. Hydrogen bonding between the sulfonamide N-H group and the carb-oxy-lic acid O atom assembles the dimers into thick layers parallel to (100). The naphthalene groups of adjacent layers are arranged in a herring-bone motif. There are C-H⋯π inter-actions between the naphthalene rings of neighbouring laye ...[more]

PMID: 25844218

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