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2-(Naphthalen-1-yl-amino)-cyclo-hexa-nol.

ABSTRACT: The title compound, C(16)H(19)NO, was synthesized under solvent-free conditions by reaction of 7-oxa-bicyclo-[4.1.0]heptane and naphthalen-1-amine in the presence of Ca(CF(3)COO)(2) as catalyst. The cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked by inter-molecular N-H?O hydrogen bonds and C-H?? inter-actions into chains parallel to the c axis.

SUBMITTER: Outouch R

PROVIDER: S-EPMC3152018 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

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2-(Naphthalen-1-yl-amino)-cyclo-hexa-nol.

Outouch Rachid R Boualy Brahim B Ali Mustapha Ait MA Firdoussi Larbi El LE Rizzoli Corrado C

Acta crystallographica. Section E, Structure reports online 20110611 Pt 7

The title compound, C(16)H(19)NO, was synthesized under solvent-free conditions by reaction of 7-oxa-bicyclo-[4.1.0]heptane and naphthalen-1-amine in the presence of Ca(CF(3)COO)(2) as catalyst. The cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked by inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions into chains parallel to the c axis. ...[more]

PMID: 21837034

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1-(3-p-Tolyl-isoxazol-5-yl)cyclo-hexa-nol.

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Crystal structure of 4-{[(naphthalen-2-yl)sulfonyl-amino]-meth-yl}cyclo-hexa-necarb-oxy-lic acid.

Project description:The title compound, C18H21NO4S, is a new sulfonamide derivative of tranexamic acid. In the crystal, mol-ecules form inversion dimers via O-H?O hydrogen bonds involving the carb-oxy-lic acid groups. Hydrogen bonding between the sulfonamide N-H group and the carb-oxy-lic acid O atom assembles the dimers into thick layers parallel to (100). The naphthalene groups of adjacent layers are arranged in a herring-bone motif. There are C-H?? inter-actions between the naphthalene rings of neighbouring layers.

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Project description:The crystal structure of the title compound, C(12)H(14)ClNO, was determined in order to confirm that the chiral center of the mol-ecule has an S configuration. The cyclo-hexa-none ring adopts a chair conformation. The 2-chloro-phenyl ring is slightly twisted from the axial C-N bond, with a N-C-C-C torsion angle of -5.7?(2)°. In the crystal, an inter-molecular N-H?O hydrogen bond links adjacent mol-ecules into an infinite chain, which propagates in the b-axis direction.

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