Ontology highlight
ABSTRACT:
SUBMITTER: Li XY
PROVIDER: S-EPMC4358338 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Li Xiao-Yong XY Harrison Melissa M MM Villalta Jacqueline E JE Kaplan Tommy T Eisen Michael B MB
eLife 20141014
We describe the genome-wide distributions and temporal dynamics of nucleosomes and post-translational histone modifications throughout the maternal-to-zygotic transition in embryos of Drosophila melanogaster. At mitotic cycle 8, when few zygotic genes are being transcribed, embryonic chromatin is in a relatively simple state: there are few nucleosome free regions, undetectable levels of the histone methylation marks characteristic of mature chromatin, and low levels of histone acetylation at a r ...[more]