Ontology highlight
ABSTRACT:
SUBMITTER: Sysoev VO
PROVIDER: S-EPMC4935972 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Sysoev Vasiliy O VO Fischer Bernd B Frese Christian K CK Gupta Ishaan I Krijgsveld Jeroen J Hentze Matthias W MW Castello Alfredo A Ephrussi Anne A
Nature communications 20160705
The maternal-to-zygotic transition (MZT) is a process that occurs in animal embryos at the earliest developmental stages, during which maternally deposited mRNAs and other molecules are degraded and replaced by products of the zygotic genome. The zygotic genome is not activated immediately upon fertilization, and in the pre-MZT embryo post-transcriptional control by RNA-binding proteins (RBPs) orchestrates the first steps of development. To identify relevant Drosophila RBPs organism-wide, we ref ...[more]