Ontology highlight
ABSTRACT:
SUBMITTER: Hamm DC
PROVIDER: S-EPMC6303782 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Hamm Danielle C DC Harrison Melissa M MM
Open biology 20181201 12
The onset of metazoan development requires that two terminally differentiated germ cells, a sperm and an oocyte, become reprogrammed to the totipotent embryo, which can subsequently give rise to all the cell types of the adult organism. In nearly all animals, maternal gene products regulate the initial events of embryogenesis while the zygotic genome remains transcriptionally silent. Developmental control is then passed from mother to zygote through a process known as the maternal-to-zygotic tra ...[more]