Ontology highlight
ABSTRACT:
SUBMITTER: Zhang TB
PROVIDER: S-EPMC4360479 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20150316
As one of the most crucial properties of DNA, the structural stability and the mechanical strength are attracting a great attention. Here, we take advantage of high force resolution and high special resolution of Atom Force Microscope and investigate the mechanical force of DNA duplexes. To evaluate the base pair hydrogen bond strength and base stacking force in DNA strands, we designed two modes (unzipping and stretching) for the measurement rupture forces. Employing k-means clustering algorith ...[more]