Ontology highlight
ABSTRACT:
SUBMITTER: Holley RJ
PROVIDER: S-EPMC4375938 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Holley Rebecca J RJ Tai Guangping G Williamson Andrew J K AJ Taylor Samuel S Cain Stuart A SA Richardson Stephen M SM Merry Catherine L R CL Whetton Anthony D AD Kielty Cay M CM Canfield Ann E AE
Stem cell reports 20150213 3
Mesenchymal progenitor cells have great therapeutic potential, yet incomplete characterization of their cell-surface interface limits their clinical exploitation. We have employed subcellular fractionation with quantitative discovery proteomics to define the cell-surface interface proteome of human bone marrow mesenchymal stromal/stem cells (MSCs) and human umbilical cord perivascular cells (HUCPVCs). We compared cell-surface-enriched fractions from MSCs and HUCPVCs (three donors each) with adul ...[more]