Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC4393732 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Wang Yan Y Jia Haiquan H Lin Huiyun H Tan Xiaogang X Du Zhiyan Z Chen Huihua H Xu Yuanji Y Han Xiaoxi X Zhang Jiakai J Zhao Siyang S Yu Xiaodan X Lu Yinglin Y
Journal of cellular and molecular medicine 20121201 12
Metastasis is a major cause of death from malignant diseases, and the underlying mechanisms are still largely not known. A detailed probe into the factors which may regulate tumour invasion and metastasis contributes to novel anti-metastatic therapies. We previously identified a novel metastasis-associated gene 1 (mag-1) by means of metastatic phenotype cloning. Then we characterized the gene expression profile of mag-1 and showed that it promoted cell migration, adhesion and invasion in vitro. ...[more]