Ontology highlight
ABSTRACT:
SUBMITTER: Bertino G
PROVIDER: S-EPMC4393929 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bertino Gaetano G Demma Shirin S Ardiri Annalisa A Proiti Maria M Mangia Alessandra A Gruttadauria Salvatore S Toro Adriana A Di Carlo Isidoro I Malaguarnera Giulia G Bertino Nicoletta N Malaguarnera Mariano M Malaguarnera Michele M
BioMed research international 20150329
<h4>Background</h4>Hepatocellular carcinoma is a major health problem worldwide and the third most common cause of cancer-related death. HCC treatment decisions are complex and dependent upon tumor staging. Several molecular targeted agents have been evaluated in clinical trials in advanced HCC. Despite of only modest objective response rates according to the Response Evaluation Criteria in Solid Tumors, several studies showed encouraging results in terms of prolongation of the time to progressi ...[more]