Ontology highlight
ABSTRACT:
SUBMITTER: Lu W
PROVIDER: S-EPMC4403228 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Lu Wei W Han Lei L Su Le L Zhao Jing J Zhang Yun Y Zhang ShangLi S Zhao BaoXiang B Miao JunYing J
Stem cells and development 20150113 9
The 3' untranslated region (UTR)-associated RNAs (uaRNAs) have important roles in various biological processes, especially in development. However, since they overlap with protein-coding mRNAs, uaRNAs are difficult to study by RNA interference techniques. We recently identified a chemical molecule, 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one (3BDO), that could efficiently induce human embryonic stem cells (hESCs) differentiation, and meanwhile selectively and efficiently downregu ...[more]