Ontology highlight
ABSTRACT:
SUBMITTER: Hover LD
PROVIDER: S-EPMC4406393 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Hover Laura D LD Abel Ty W TW Owens Philip P
Translational oncogenomics 20150415
Glioblastoma multiforme (GBM) is a grade IV glioma with a median survival of 15 months. Recently, bone morphogenetic protein (BMP) signaling has been shown to promote survival in xenograft murine models. To gain a better understanding of the role of BMP signaling in human GBMs, we examined the genomic alterations of 90 genes associated with BMP signaling in GBM patient samples. We completed this analysis using publically available datasets compiled through Te Cancer Genome Atlas and the Glioma M ...[more]