Ontology highlight
ABSTRACT:
SUBMITTER: Kodani SD
PROVIDER: S-EPMC4407705 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Kodani Sean D SD Hammock Bruce D BD
Drug metabolism and disposition: the biological fate of chemicals 20150311 5
Dr. Bernard Brodie's legacy is built on fundamental discoveries in pharmacology and drug metabolism that were then translated to the clinic to improve patient care. Similarly, the development of a novel class of therapeutics termed the soluble epoxide hydrolase (sEH) inhibitors was originally spurred by fundamental research exploring the biochemistry and physiology of the sEH. Here, we present an overview of the history and current state of research on epoxide hydrolases, specifically focusing o ...[more]