Ontology highlight
ABSTRACT:
SUBMITTER: Knapp S
PROVIDER: S-EPMC4411934 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Knapp Susanne S Meghjee Naeem N Cassidy Sorcha S Jamil Khaleel K Thursz Mark M
BMC medical genetics 20141005
<h4>Background</h4>Variants of the interferon-lambda3 (IFNL3) gene have been associated with both spontaneous and treatment induced clearance of HCV infection. Attempts to link polymorphisms of the IFNL3 gene with variation in the level of IFNL3 expression have been inconclusive. This is partially due to the difficulty to design assays distinguishing IFNL3 from IFNL2.<h4>Methods</h4>In this study an allele specific real-time PCR (RT-PCR) assay was developed which allows the relative quantificati ...[more]