Genetics, genomics and evolution of ergot alkaloid diversity.
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ABSTRACT:
SUBMITTER: Young CA
PROVIDER: S-EPMC4417967 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Genetics, genomics and evolution of ergot alkaloid diversity.
Young Carolyn A CA Schardl Christopher L CL Panaccione Daniel G DG Florea Simona S Takach Johanna E JE Charlton Nikki D ND Moore Neil N Webb Jennifer S JS Jaromczyk Jolanta J
Toxins 20150414 4
The ergot alkaloid biosynthesis system has become an excellent model to study evolutionary diversification of specialized (secondary) metabolites. This is a very diverse class of alkaloids with various neurotropic activities, produced by fungi in several orders of the phylum Ascomycota, including plant pathogens and protective plant symbionts in the family Clavicipitaceae. Results of comparative genomics and phylogenomic analyses reveal multiple examples of three evolutionary processes that have ...[more]
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