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Complete Closed Genome Sequences of a Mannheimia haemolytica Serotype A1 Leukotoxin Deletion Mutant and Its Wild-Type Parent Strain.


ABSTRACT: Mannheimia haemolytica is a bacterial pathogen that secretes leukotoxin (LktA) which binds to leukocyte membranes via CD18, causing bacterial pneumonia in ruminants. We report the complete closed genome sequences of a leukotoxin mutant and its parent strain that are frequently used in respiratory disease studies.

SUBMITTER: Heaton MP 

PROVIDER: S-EPMC4424311 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Complete Closed Genome Sequences of a Mannheimia haemolytica Serotype A1 Leukotoxin Deletion Mutant and Its Wild-Type Parent Strain.

Heaton Michael P MP   Harhay Gregory P GP   Smith Timothy P L TP   Bono James L JL   Chitko-McKown Carol G CG  

Genome announcements 20150507 3


Mannheimia haemolytica is a bacterial pathogen that secretes leukotoxin (LktA) which binds to leukocyte membranes via CD18, causing bacterial pneumonia in ruminants. We report the complete closed genome sequences of a leukotoxin mutant and its parent strain that are frequently used in respiratory disease studies. ...[more]

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