Ontology highlight
ABSTRACT:
SUBMITTER: Dietrich M
PROVIDER: S-EPMC4428587 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Dietrich Manuela M Mollenkopf Hans H So Magdalene M Friedrich Alexandra A
FEMS microbiology letters 20090508 2
The ATPase protein PilT mediates retraction of type IV pili (Tfp). Tfp retraction of Neisseria gonorrhoeae causes many signal transduction events and changes in gene expression in infected epithelial cells. To find out whether a pilT mutation and lack of Tfp retraction, respectively, lead also to gene regulation in bacteria, we performed microarrays comparing the transcriptional profiles of the N. gonorrhoeae parent strain MS11 and its isogenic pilT mutant during growth in vitro. A loss-of-funct ...[more]