Ontology highlight
ABSTRACT:
SUBMITTER: Rieckher M
PROVIDER: S-EPMC4441442 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Rieckher Matthias M Kyparissidis-Kokkinidis Ilias I Zacharopoulos Athanasios A Kourmoulakis Georgios G Tavernarakis Nektarios N Ripoll Jorge J Zacharakis Giannis G
PloS one 20150522 5
We describe a customizable and cost-effective light sheet microscopy (LSM) platform for rapid three-dimensional imaging of protein dynamics in small model organisms. The system is designed for high acquisition speeds and enables extended time-lapse in vivo experiments when using fluorescently labeled specimens. We demonstrate the capability of the setup to monitor gene expression and protein localization during ageing and upon starvation stress in longitudinal studies in individual or small grou ...[more]