Ontology highlight
ABSTRACT:
SUBMITTER: Enriquez J
PROVIDER: S-EPMC4441546 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Enriquez Jonathan J Venkatasubramanian Lalanti L Baek Myungin M Peterson Meredith M Aghayeva Ulkar U Mann Richard S RS
Neuron 20150507 4
How the highly stereotyped morphologies of individual neurons are genetically specified is not well understood. We identify six transcription factors (TFs) expressed in a combinatorial manner in seven post-mitotic adult leg motor neurons (MNs) that are derived from a single neuroblast in Drosophila. Unlike TFs expressed in mitotically active neuroblasts, these TFs do not regulate each other's expression. Removing the activity of a single TF resulted in specific morphological defects, including m ...[more]