Ontology highlight
ABSTRACT:
SUBMITTER: Singleman C
PROVIDER: S-EPMC4446259 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Singleman Corinna C Holtzman Nathalia G NG
Developmental dynamics : an official publication of the American Association of Anatomists 20121105 12
<h4>Background</h4>Cardiac maturation is vital for animal survival and must occur throughout the animal's life. Zebrafish are increasingly used to model cardiac disease; however, little is known about how the cardiovascular system matures. We conducted a systematic analysis of cardiac maturation from larvae through to adulthood and assessed cardiac features influenced by genetic and environmental factors.<h4>Results</h4>We identified a novel step in cardiac maturation, termed cardiac rotation, w ...[more]