Ontology highlight
ABSTRACT:
SUBMITTER: Xie T
PROVIDER: S-EPMC4456287 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Xie Tao T Zmyslowski Adam M AM Zhang Yongbo Y Radhakrishnan Ishwar I
Structure (London, England : 1993) 20150507 6
Chromatin-binding proteins play vital roles in the assembly and recruitment of multi-subunit complexes harboring effector proteins to specific genomic loci. MRG15, a chromodomain-containing chromatin-binding protein, recruits diverse chromatin-associated complexes that regulate gene transcription, DNA repair, and RNA splicing. Previous studies with Pf1, another chromatin-binding subunit of the Sin3S/Rpd3S histone deacetylase complex, defined the sequence and structural requirements for interacti ...[more]