Ontology highlight
ABSTRACT:
SUBMITTER: Chen JJ
PROVIDER: S-EPMC4463613 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20150429 5
Three new coumarin derivatives, 8-formylalloxanthoxyletin (1), avicennone (2), and (Z)-avicennone (3), have been isolated from the stem bark of Zanthoxylum avicennae (Z. avicennae), together with 15 known compounds (4-18). The structures of these new compounds were determined through spectroscopic and MS analyses. Compounds 1, 4, 9, 12, and 15 exhibited inhibition (half maximal inhibitory concentration (IC₅₀) values ≤7.65 µg/mL) of superoxide anion generation by human neutrophils in response to ...[more]